Hodgkin lymphoma in children and adolescents: improving the therapeutic index
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چکیده
منابع مشابه
Hodgkin lymphoma in children and adolescents: improving the therapeutic index.
Hodgkin lymphoma (HL) is a highly curable form of childhood cancer, with estimated 5 year survival rates exceeding 98%. However, the establishment of a "standard of care" approach to its management is complicated by the recognition that long-term overall survival declines in part from delayed effects of therapy and that there continue to be subgroups of patients at risk for relapse for which pr...
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Hodgkin lymphoma (HL) accounts for about 10% of all childhood cancers. Five-year survival rates with modern therapies are now approaching >90-95% as a consequence of its significant sensitivity to both chemotherapy and radiation. The current challenge is to determine how much therapy is needed to improve survival and how to adapt treatment to the patient to prevent these long term toxicities. T...
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Englund, A. 2017. Hodgkin Lymphoma in children, adolescents and young adults. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1314. 67 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9851-1. Hodgkin lymphoma (HL) is a heterogeneous condition varying from engaging one single lymph node site to a widespread condition. The prognosis with contempor...
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Background and Objectives: Classic Hodgkin lymphoma (CHL), anaplastic large cell lymphoma (ALCL) and some cases of diffuse large B cell lymphoma (DLBCL) have overlapping morphologic features. Since they all represent distinct clinico-pathologic entities, we explored the differential diagnostic impact of immunophenotyping to discriminate between them. Materials and Methods:...
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correlation of genetic VT risk with the plasma levels of the fibrinogen variant suggests that FGG-H2 and -H3 haplotypes modify thrombosis risk by controlling the level of this FGG splice isoform. In response to our manuscript, Cheung and coworkers note that elevated fibrinogen ratios are associated with cardiovascular diseases and acute phase reaction but not with clinical outcome. This is an i...
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ژورنال
عنوان ژورنال: Hematology
سال: 2015
ISSN: 1520-4391,1520-4383
DOI: 10.1182/asheducation.v2015.1.514.3917878